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Make sure theres a way to get a quick response from a licensed practitioner (ideally someone trained in obesity medicine) if you dont feel well or have questions, like by messaging through a patient portal

Insufficient treatment duration is among the most common explanations

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It can cause irritation, inflammation, and pain in the rectal area
Addressing the "great unknowns" of HS require a deeper investigation into the functional duality of MMPs and TIMPs
