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Intracellular cAMP sensor EPAC: Physiology, pathophysiology, and therapeutics development

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A new study presented at the 2025 Annual Meeting of the American Academy of Orthopaedic Surgeons examined how the timing of a patients last dose of a GLP-1 agonists prior to total knee arthroplasty (TKA) or total hip arthroplasty (THA) influences anesthesia-related complications such as delayed emergence, aspiration, aspiration pneumonitis, and conversion to intubation

These animal models have also explored whether G protein-coupled taste receptor expression is altered in obesity models, particularly in leptin-deficient ob/ob mice and diet-induced obesity models (122)

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