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The Judicial Panel on Multidistrict Litigation has ordered all federal lawsuits alleging vision loss from Ozempic, Wegovy, and related GLP-1 drugs to be centralized in the Eastern District of Pennsylvania

The report tracks competitive developments, strategies, mergers and acquisitions and new product development

Accessed March 7, 2024.

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Pharmaceutical Economics 101 Brand-Name Drug Costs Include: Research & Development: Clinical trial costs: $2-3 billion per drug Years of research before approval Failed drug candidates FDA approval process Amortized across all units sold Manufacturing & Facilities: Large-scale FDA-approved manufacturing Extensive quality control Regulatory compliance costs Facility maintenance and upgrades Marketing & Sales: Direct-to-consumer advertising (billions annually) Physician detailing and sales force Medical education programs Brand building campaigns Profit Margins: Shareholder returns expected Executive compensation Wall Street expectations Quarterly earnings targets Distribution: Pharmacy benefit managers (PBMs) Wholesalers and distributors Multiple middlemen taking cuts Rebates and discounts (complex system) Eli Lillys tirzepatide list price of $1,069/month reflects all these costs plus significant profit margins