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If significant declines are observed, doses should be adjusted
Patients should avoid extreme temperature changes when possible and be particularly cautious in cold weather, as reduced cold tolerance may increase risk of hypothermia during prolonged exposure
Fertility can improve with weight loss and improved metabolic health, and some people conceive unexpectedly
GLP-1 receptor agonists are the most expensive drug class by total spend for commercial plans
doi:10.1016/j.neures.2014.02.002 126
