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However, this method often hides the connection between cause and effect

In the STEP 1 semaglutide trial (Wilding et al., NEJM , 2021) and the SURMOUNT-1 tirzepatide trial (Jastreboff et al., NEJM , 2022), nausea affected roughly 44% of semaglutide patients and about 24% of tirzepatide patients at the maximum dose

Researchers replicating this low-dose arm in their own work can complete the entire weekly-dose protocol from one vial

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2 Due to PD predominantly being a disease associated with depletion of dopamine, current therapies focus on repleting, mimicking, or preventing the degradation of this neurotransmitter