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For eligible patients, it may be prescribed as part of a clinician-guided weight-management plan

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These medications: reduce appetite lower inflammation improve liver fat improve metabolic markers reduce cardiovascular events (SELECT trial) They do not : build muscle increase VO max improve mitochondrial function replace strength training fix metabolic flexibility guarantee long-term weight maintenance 2
doi: 10.1016/j.neuron.2017.09.042 109 HardieDG
