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According to Truveta Research presented at ISPOR 2025, side effects were the leading reason patients stopped taking GLP-1 medications, accounting for 28.2% of all discontinuations

Lu Y, Liu Y, Krumholz HM

Berberine structure BBR is an isoquinoline alkaloid, and it is a quaternary amine with the molecular formula C 20 H 18 NO 4 + (2,3 methylenedioxy-9,10-dimethoxyprotoberberine chloride) and a molecular weight of 336.37 g/mol (Fig

10.1016/j.biopha.2024.117464 24 GuptaM
