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Endocrinology 155 (4), 12801290

GLP1 receptor agonists have transformed obesity and weight management

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For some patients, this may begin with bodyweight movements, bands, supervised training, or physical therapy-style progression

Glucagon receptor activation introduces a distinct mechanism it increases energy expenditure through thermogenic signalling in adipose and hepatic tissue which operates independently of the appetite-regulating effects attributed to GLP-1R engagement