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The presence of GLP-1R on vagal afferent nerves plays a key role in this effect

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No blinding was used in the initial mouse study, though the CROs conducting the second mouse study and the NHP study were blinded to the antibodies we supplied

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[PubMed ID: 29773502]

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GLP-1 elife SNSGLP-1 elife elife elife elife elife elife1 GLP-1 elifeGLP-1 elife GLP-1 elifeGLP-1 GLP-1 elife PC GLP-1 GLP-1 elife elife elife () GLP-1 1 elife GLP-1 11 () elife 11 () 1 OK GLP-1 11 () elife 13 SGLT-2 GLP-1 elife4 11 eLifeGLP-1 () AGA () eLife elife elife 0 0 elife elife elifeHP 24OK 7:0023:30 PC OK elife elife 1 1 2 2GLP-1 3 3 4 4elife 5 5elife elife GLP-1 elifeGLP-1 GLP-1 1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1GLP-1 GLP-1 GLP-1 GLP-1 GLP-1GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 GLP-1 Q1

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Agonistas duales de receptores GLP-1 y GIP en la diabetes tipo 2: mecanismos de accin y bases fisiopatolgicas

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