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GLP-1 therapies have demonstrated substantial weight-reduction benefits, with studies showing an average weight loss of 4.6 kg, a BMI reduction of 2.1 kg/m, and a decrease in waist circumference of 4.6 cm compared to placebo

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doi: 10.1001/jamainternmed.2023.7268

Lilly intends to submit the drug to regulators by the end of 2025, positioning it as the first oral GLP-1 receptor agonist approved specifically for obesity

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