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Body weight was reduced by 9.8% in the semaglutide group compared with 3.4% in the placebo group

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The key question is whether that receptor combination can produce useful metabolic effects while maintaining an acceptable safety profile

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The GLP-1 elevations observed with allulose consumption are generally small and transient compared to those achieved with pharmaceutical GLP-1 receptor agonists such as semaglutide or liraglutide, which produce sustained and pharmacologically significant increases in GLP-1 activity

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