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You may find that: Portions feel naturally smaller Cravings decrease Eating feels more controlled without effort Weight loss may still be minimal at this stage, especially since semaglutide is usually started at a low dose

Large overage (more than 5 mg over): This is a medical situation

Using the medication beyond the 28-day mark increases the risk of reduced potency, which could affect weight loss results and metabolic control

Reconstituted : Once reconstituted using sterile diluent, solutions should be kept refrigerated at 28C and used within the timeframe specified by the research protocol, typically within 2830 days

Your healthcare team should also review your complete medication list, as stopping tirzepatide may require adjustments to other therapies