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[DOI] [PMC free article] [PubMed] [Google Scholar] 119.Cai H., Cong W.N., Daimon C.M., Wang R., Tschp M.H., Svigny J., Martin B., Maudsley S

These are more likely to occur within the first weeks of initiation of therapy and with dose escalation

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Therefore, the observed ROR/PRR elevations indicate signal strength rather than incidence or causal relation

While it was initially reported that mice deficient in Insl5 were mildly glucose-intolerant (170), this appears to be age (170) and strain-dependent (164, 168)
