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[DOI] [PubMed] [Google Scholar] 7.Once-weekly semaglutide in adults with overweight or obesity

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Finally, in the ELIXA trial, the GLP-1 receptor agonist lixisenatide was shown to reduce UACR by 39% in people with macroalbuminuria at baseline, despite very modest effects on hemoglobin A 1c (0.3%) and body weight (0.7 kg) (13)

Introduction The glucagon-like peptide-1 (GLP-1) is a 3031 amino acid incretin secreted by enteroendocrine L cells in the ileum and colon in response to nutritional stimuli such as glucose, fatty acids, and amino acids in the intestinal lumen

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