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Available online at: 209.Athauda D, Maclagan K, Skene SS, Bajwa-Joseph M, Letchford D, Chowdhury K, et al

The GPR84 GLP-1 mechanism described here has been demonstrated in mouse models and enteroendocrine cell lines (Nonaka et al., 2022

The guideline emphasises a stepwise approach to treatment intensification, typically progressing from metformin monotherapy to dual therapy (often with an SGLT2 inhibitor, DPP-4 inhibitor, pioglitazone, or sulphonylurea), and then to triple therapy or insulin-based regimens
The vitamin is crucial for myelin synthesis, the protective sheath surrounding nerve fibres

Maintaining adequate hydration while taking Wegovy is therefore particularly important for those with gout risk factors
