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Abbreviations AUC: Area under the curve CR: Calorie restriction GSIS: Glucose-stimulated insulin secretion HFD: High-fat diet HOMA-IR: Homeostasis model assessment quantified insulin resistance IPGTT: Intraperitoneal glucose tolerance test PA: Palmitic acid PDX-1: Pancreatic duodenal homeobox 1 SME: Semaglutide T2DM: Type 2 diabetes mellitus References Chooi YC, Ding C, Magkos F

Weight loss can improve self-esteem and body image and may also reduce symptoms of depression and anxiety

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Whilst an accidental double dose is not typically life-threatening, it significantly increases the risk of adverse effects, particularly gastrointestinal symptoms and low blood sugar

It regulates blood sugar by boosting insulin secretion, reducing glucagon release, and slowing digestion to promote satiety