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As shown in Figure 3C, the estrous cycle of the normal control group mice was maintained within the physiological range of 45 days, while the PCOS model group mice showed sustained elongation of the estrous cycle
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For glycemic control in type 2 diabetes, measurable reductions in hemoglobin A1c typically become apparent within 4-8 weeks, with maximum effects often seen at 12-16 weeks

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Research shows that post-surgical changes in bile acid metabolism can influence weight loss outcomes and medication tolerance
