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Nausea and vomiting, common side effects of GLP-1 therapy, can lead to volume depletion, further straining kidney function when paired with medications that inhibit the renin-angiotensin system (RAAS)

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Retatrutide is an investigational triple incretin receptor agonist targeting GLP-1, GIP, and glucagon receptors currently in Phase 3 trials with no global regulatory approval

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Probable Mechanisms of the Beneficial Effects of GLP-1 and GIP/GLP-1 Receptor Agonists in the Lung Both GLP-1 and GIP receptors can be found in the lung

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Proteome raw files were searched using Fragpipe using SEQUEST search engine and the SwissProt rat database

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