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Journal of Orthopaedic Surgery and Research

The researchers examined how the drugs affected patients cardiorespiratory fitnesshow strongly the heart performs, how efficiently the lungs take in oxygen and how effectively muscles use that oxygen

This causes: Increased membrane permeability Tubular cell injury and necrosis GFR Result: Acute tubular necrosislike picture 2 Renal vasoconstriction (hemodynamic effect) Amphotericin B causes afferent arteriolar vasoconstriction

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Endocrine, 87(1), 159-169