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113 Intestinal flora disorders may compromise the BBB integrity due to the decreased expression of tight junction proteins

Once weight stabilises and the medication is discontinued, the additional GLP-1-driven risk diminishes

Increase your dietary protein intake Aim for 20 to 30 grams of protein at each meal, or 1 to 1.5 grams of protein per kilogram of body weight daily

However, when it is in excess, these benefits are overcome by a pro-inflammatory activity, being associated with worse haemodynamic and metabolic profile in patients affected by HFpEF [35, 36]

Some people have a dramatic response, some people don't notice much of anything