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GLP-1R/GIPR-Targeting Drugs GLP-1 Peptide Drugs Novo Nordisk's semaglutide-based medicinesWegovy, Ozempic, and Rybelsushave significantly advanced the management of obesity and type 2 diabetes

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Tirzepatides sequence includes two aminoisobutyric acid (Aib) residues, which slow enzymatic breakdown and improve stability
PMID: 3569763 DOI: 10.1016/0016-5085(87)90619-6 Runde TJ, Nappe TM (2023): Salicylates Toxicity
