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[DOI] [PubMed] [Google Scholar] [6].Baggio LL, Drucker DJ, Biology of incretins: GLP-1 and GIP, Gastroenterology, 132 (2007) 21312157

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GLP-1R activation exerted antifibrotic effects by blocking the interaction between the NLPR3 inflammasome and PFKFB3-driven glycolysis, leading to the inhibition of lactate production and subsequent histone lactylation, and thereby decreasing profibrotic gene expression in fibroblasts under inflammatory stress

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Insulin resistance is a medical condition commonly associated with PMOS

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Wegovy (semaglutide): Injection for weight loss

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Como explicacin de este efecto adverso, se ha propuesto que el retraso del vaciamiento gstrico y la sensacin de saciedad, al traer como consecuencia lgica la disminucin de la ingesta de alimentos y agua, provoca disminucin en la frecuencia en las deposiciones 4

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