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Relatedly, a new First Opinion essay takes issue with the all-or-nothing approach to the medically frail exemption in the new Medicaid work requirements

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Evidence: A clinical study presented at the European Society for Paediatric Endocrinology (2024) found that combining Metformin with a GLP-1 analog improved weight outcomes compared to either drug alone Safety: The MetforminGLP-1 combination for weight loss is generally well-tolerated

This article examines the evidence for lipid-modifying effects, identifies who may benefit, and clarifies how GLP-1 agents compare with traditional cholesterol-lowering treatments within UK clinical practice