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And the side effects were ones that are widely known with these medicines: mainly gastrointestinal disorders like nausea, diarrhea, vomiting and constipation, which usually affected people in the first few months of the study as the dose of the medicine increased

However, thousands of people were prescribed the drug before these warning label updates

Some people do, but short-term use without lifestyle change often leads to regain

The news marks a shift in thinking about orthopedic treatment

The intensity of these effects usually reaches its highest point between days 7 and 14 of the first dose, as your gastrointestinal system adapts to the medication's mechanism