glp 1 receptor brain GLP-1 programs the neurovascular landscape: Cell Metabolism Frontiers | GLP-1 Suppresses Feeding

The concern would be, the genetic change would be permanent so if there is over-expression which may change with various states weight loss, illness, aging, hormonal changes it could cause problems from over-expression with no way to reverse, except remove the pancreas or treated muscle, Kohn said in an email

doi: 10.1016/j.neuroscience.2010.08.028

There is early research on experimental GLP-1 patches for various conditionsusing advanced microneedle delivery systems, but these remain in preclinical stages

Its discouraging. In clinical trials, most participants taking Wegovy or Mounjaro to treat obesity lost an average of 15% to 22% of their body weight up to 50 pounds or more in many cases

The GLP-1 story is still unfolding, but the early receipts are in