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Finding a way to increase the biological half-life of GLP-1 or using GLP-1 analogs could be a step in the right direction to expand the treatment options for UC

Bibliografia Fras JP, Davies MJ, Rosenstock J, Prez Manghi FC, Fernndez Land L, Bergman BK, et al

These benefits may be attributed to improved glycemic control, weight loss, reduced inflammation, and direct effects on blood vessels and the heart
These findings were confirmed in high-fat, high-cholesterol (HFHC) dietfed mice with functional LDL receptor deficiency induced by viral expression of proprotein convertase subtilisin/kexin type 9adeno-associated virus (PCSK9-AAV), in which daily administration of semaglutide for 18 weeks reduced aortic plaque area (11)
Transection of the oesophagus for bleeding oesophageal varices
