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Controlled-release phentermine/topiramate in severely obese adults: a randomized controlled trial (EQUIP) Obesity (Silver Spring) 2012;20(2):330342

To put this into context, Ozempic was first approved (for diabetes) in 2017

J Glob Antimicrob Resist

Burmeister MA, Ayala JE, Smouse H, Landivar-Rocha A, Brown JD, Drucker DJ, Stoffers DA, Sandoval DA, Seeley RJ, Ayala JE

M., Abbasi, B., Hakam, N., & Breyer, B
