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Individual variation matterssome patients may tolerate longer intervals better than others, particularly if they have genetic variations in GLP-1 receptor sensitivity

Comparability studies are required when there are changes in the manufacturing process or formulation

This keeps the focus on execution rather than labels

Randomized placebo-controlled study comparing semaglutide with liraglutide and placebo in 957 non-diabetic, obese adults that showed greater weight loss with semaglutide compared with liraglutide