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If your primary issue is a plateau on semaglutide, a permanent switch to tirzepatide is supported by stronger evidence than alternating

Though its intended purpose is to moderate insulin levels in diabetics, new users are overwhelmingly adopting the drug for its notable weight loss side effects

[DOI] [PMC free article] [PubMed] [Google Scholar] 56.Nexe-Larsen C.C., Srensen P.H., Hausner H., Agersnap M., Baekdal M., Brnden A., Gustafsson L.N., Sonne D.P., Vedtofte L., Vilsbll T., et al

Beyond these established indications, accumulating evidence suggests that GLP-1 RAs exert pleiotropic effects on immune regulation, inflammation, and tissue remodelingpathways highly relevant to dermatological and surgical disciplines [1,2,3,4,5]

Neurosci Lett (2001) 303(2):7982
