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Constipation affects 21% of Retatrutide users

If oral semaglutide is considered to be similarly safe and effective relative to currently available treatments T2DM, at a submitted price of $6.97 per tablet (daily cost of $6.97), oral semaglutide is more costly than all sodium-glucose cotransporter-2-based products ($2.45 to $3.24), dipeptidyl peptidase-4-based products ($2.20 to $3.47), and, depending on dose, some GLP-1 receptor agonist-based products ($3.55 to $9.34)
doi: 10.1016/j.ejphar.2022.175175 81 GengJShiYZhangJYangBWangPYuanWet al

While operating on GLP-1 patients (who might need body lifts or tummy tucks following rapid weight loss), plastic surgeons are noticing a marked difference in their skin quality, with collagen and elastin fibers that can be thinner and weaker than expected

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