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In individuals with type 2 diabetes, liraglutide treatment results in a weight loss of 1.38.6 kg and a 0.92.2% (9.924.2 mmol/mol) reduction in HbA 1c , relative to baseline [27]

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Although direct evidence for GLP-1RA use in PsA remains limited, the inclusion of PsA populations in these tirzepatide trials represents a conceptual shift toward testing immunometabolic interventions in inflammatory arthritis rather than restricting their evaluation to skin disease alone

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