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40 In the LIVE trial, which evaluated the effects of liraglutide on LV function in stable chronic HF patients with and without diabetes, at the end of treatment patients from the liraglutide group were able to walk 28 65 m longer during the 6MWT, compared with 3 89 m for patients in the placebo group, with a mean difference of 24 m

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As per a 72-week double-blind controlled trial, patients given weekly subcutaneous tirzepatide had significant, lasting weight loss versus placebo