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Weight loss results vary and depend on diet, physical activity, and consistent use of the medication
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Consistent observation and modifications are crucial for optimizing the advantages of certain therapies when using them together

However, spontaneous reporting systems are subject to substantial limitations, including under-reporting, confounding by indication (e.g., diabetes-related xerostomia), channeling bias toward older or more comorbid patients, and polypharmacy involving xerostomia-inducing drugs such as antidepressants and anticholinergics