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At the end of 2016, the Amgen team filed a patent (US20170275370A1) titled "Methods for Treating or Ameliorating Metabolic Disorders Using a GIPR Binding Protein in Combination with a GLP-1 Agonist." This reported the therapeutic potential of using an antibody targeting the GIPR in combination with a GLP-1 receptor agonist for the treatment of type 2 diabetes, obesity, dyslipidemia, elevated levels of glucose, increased insulin levels, and diabetic nephropathy