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The effects on lipids are likely to reflect slowed gastric emptying and reduced delivery for absorption, as well as impact on hepatic and fat cell metabolism

Clinical Practice Guidelines American Diabetes Association (ADA): Recommends GLP-1 agonists as long-term therapy No suggested stopping point for effective treatment Emphasizes individualized, ongoing assessment Obesity Medicine Association: Recognizes obesity as a chronic disease Supports long-term pharmacotherapy Recommends continuing treatment as long as beneficial Endocrine Society: Supports chronic use of obesity medications Emphasizes that stopping often leads to weight regain Recommends ongoing treatment for chronic weight management What the Guidelines Mean Practically The consistent message from regulatory bodies and medical societies: Ozempic is designed for long-term use

In animal models SGLT2 inhibitors have been theorized to potentially increase risk of MTC

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This is the phase where you see why the rough month 2 was worth it