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Sarcoplasmic/endoplasmic reticulum Ca2 + -ATPase 2a (SERCA2a), a pivotal protein in the excitationcontraction coupling process, maintains calcium homeostasis in cardiomyocytes by transporting Ca2+ from the cytoplasm back into the sarcoplasmic reticulum

The GLP-1/GIP dual agonist, HRS9531, from Hengrui, reported positive Phase 3 results in weight loss, and is the second (after Innovent) Chinese company to submit marketing authorisation for an obesity asset

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Oral alternatives could lower costs and improve access if they demonstrate comparable efficacy

A craving-reduction medication would come into play in the recovery phase that follows detox, as a tool to help prevent a return to heavy drinking