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The leave-one-out analysis demonstrated the effect on SBP was robust and not driven by a single study, with mean differences in SBP for individual studies varying from 4.63 to 5.04 mmHg (Supplementary Materials)

These include model phenotyping studies and the characterization of several MASH-targeted drug classes, such as GLP1R agonists (e.g., semaglutide), THR- receptor agonists (e.g., resmetirom), PPAR agonists (e.g., lanifibranor), FGF21 analogues (e.g., efruxifermin), as well as various long-acting dual GLP1R-GIPR agonists (e.g., tirzepatide) and GLP1R-GCGR agonists (e.g., survodutide)

So, the higher dose of semaglutide that youll receive with Wegovy will likely lead to slightly more significant reductions in weight loss without experiencing more adverse events or side effects

Reconstituted semaglutide must be refrigerated immediately and used within 28 days

Step 3: Plan Your Post-Wegovy Strategy Have a weight management plan ready before you stop, not after the weight starts creeping back