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While tirzepatide itself does not cause nightmares, nocturnal hypoglycemia (low blood sugar at night) can cause nightmares and sleep disturbances, particularly when tirzepatide is combined with insulin or sulfonylureas

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Eating smaller, low-fat meals can help reduce these issues

The American Diabetes Association recommends monitoring blood glucose before, during, and after alcohol consumption, including overnight monitoring due to the risk of delayed hypoglycemia