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Since the first semaglutide drug was approved in 2005, patients and manufacturers have seen many changes: shortages, compounding, and more than a thousand lawsuits from patients who experienced severe side effects under these drugs, including stomach paralysis, bowel obstruction, and vision loss

GLP-1 RAs also exhibit protective effects against cardiovascular and renal complications, making them integral to comprehensive metabolic disease management (6)(15)

They both produce meaningful, sustained weight loss results

The therapeutic benefits including appetite suppression, improved glycaemic control, and any weight loss effects will gradually diminish over the subsequent weeks as drug concentrations decline

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