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Beyond Insulin: Using Ozempic and Other Off-Label Drugs for Type 1 Diabetes GLP-1 Receptor Agonists More and more clinicians are using GLP-1s off-label in people with type 1 diabetes, particularly in those who also have obesity or high insulin requirements, says Mihail Zilbermint, MD, an associate professor of medicine at Johns Hopkins University School of Medicine and the chief of the division of endocrinology, diabetes, and metabolism at Suburban Hospital in Maryland