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Walker said

The key mechanisms are: Sustained appetite suppression and reduced caloric intake Reduced dietary variety and food volume Delayed gastric emptying Gastrointestinal side effects Rapid weight loss and lean mass reduction Potential alterations in gut microbiota Each pathway contributes differently

2 Interactions between the GLP-1 pathway and alcohol As shown in Figure 1, the accumulated preclinical findings imply that the GLP-1 pathway modulates alcohol-mediated responses, which include the following: 1) alcohol drinking, 2) alcohol-induced behaviors and neurochemistry, 3) the motivation to consume alcohol and alcohol-seeking, and 4) relapse drinking

[DOI] [Google Scholar] 32.Neel N.F., Ghobara Y., Turkmani M

The most common adverse effects were nausea, vomiting, and diarrhea during the first 4-8 weeks of treatment