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They work by directly mimicking GLP-1 hormone activity at pharmacological concentrations, are approved by regulatory agencies for specific indications, and require both a prescription and medical supervision

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Accessed March 13, 2026

In the GLP-1RAs cohort, BMI was higher (mean [SD], 37.1 [6.85] vs 35.5 [6.78]), and individuals were more likely to have a history of sleep apnoea (Table 1)