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glp-1 agonist gastroparesis Emergency Medicine Ottawa | π¨ agonists are everywhere in the ED now. Ozempic, Wegovy, Mounjaro and friends are changing Emergency Medicine, from Researchers find GLP-1 medications safe
Description
Originally approved to help manage type 2 diabetes, it has since been approved for weight loss

JorsalAKistorpCHolmagerPTougaardRSNielsenRHnselmannAet alEffect of liraglutide, a glucagon-like peptide-1 analogue, on left ventricular function in stable chronic heart failure patients with and without diabetes (LIVE)-a multicentre, double-blind, randomised, placebo-controlled trial

In non-human primates, the highest GLP-1 immunoreactivity has been demonstrated in various nuclei of the hypothalamus, the area postrema, the NTS, and the dorsal motor nucleus of the vagus [389]

Co-infusion of GLP-1 and GIP to healthy human subjects has resulted in increased insulinotropic effects [928]

Incorrect peptide content means actual dosing may be much higher or lower than intended, which directly affects both efficacy and side effect risk
