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The majority of the reported events occurred in patients who experienced gastrointestinal reactions leading to dehydration such as nausea, vomiting, or diarrhea [see Adverse Reactions (6.1)]

Subgroup analyses revealed significant associations between Paxlovid benefit and patients with cancer (NNT, 45), cardiovascular disease (30), and both conditions (16)

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GLP-1 also helps with thermogenesis and mitochondrial function in fat tissue, supporting steady energy

The addition of glucagon receptor agonism introduces a third axis: increased energy expenditure, enhanced hepatic fat oxidation, and PCSK9-mediated reduction in LDL cholesterol