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Here is the time-to-event analysis which again shows the non-fatal heart attack (MI) reduction, whereas nonfatal stroke was not significantly reduced (a 7% relative reduction)

doi: 10.1007/s13300-018-0524-z 80 Zitman-GalT.EinbinderY.OhanaM.KatzavA.KartawyA.BenchetritS

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Observational research presented in March 2026 at the American Academy of Orthopaedic Surgeons annual meeting found that GLP-1 drugs may slightly increase the risk of developing osteoporosis and gout, a kind of inflammatory arthritis caused by a buildup of uric acid