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Rapid weight loss can signal energy deficiency to the hypothalamus, potentially suppressing gonadotropin-releasing hormone (GnRH) secretion

This method is important for identifying first-time obesity-related prescriptions for all adolescents, ensuring that we track new treatment initiations while reducing the risk of including on-going prescriptions

The Canada Story Why Every Generics Company Is Watching It Closely Canada has become the most strategically significant generics market in the world for semaglutide, and the reason is almost paradoxical: its a regulated, Western market with real pricing power and yet its core patent lapsed in January 2026

5 The absolute risk increase is small (around 3 extra cases for every 1,000 people taking the medication for a year), and the effect is partly explained by weight loss rather than the medication itself