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Surg Endosc 39(1):180183

If you are experiencing a weight loss plateau on tirzepatide, discussing your genetic predispositions alongside your clinical response (weight lost, side effects, adherence, lifestyle factors) with your provider can help clarify whether dose optimization, lifestyle adjustments, or assessment of other metabolic factors are most relevant to your situation

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It includes lethargy

-10.25% at 26 weeks, p = 0.0372)
