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Although preclinical experiments suggest potential neuroprotective effects of DBS, results from clinical studies have shown that dopaminergic neuron degeneration remains unaltered (Hilker et al

If your body senses persistent GLP-1 stimulation, it may reduce production of these complementary hormones or increase production of orexigenic (hunger-promoting) signals like ghrelin

Ask about alternatives (e.g., tirzepatide, liraglutide, phentermine/topiramate) and how they fit your goals and health history

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In addition, the manifestation of adipose tissue dysfunction, with increased production of FFAs and proinflammatory cytokines, worsens insulin resistance and disease progression (60, 61) ( Figure 1 )