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But for all of those years, we continued to work with many obesity specialists all over the world who were desperate for help for their patients, and it only became worse and worse and worse in all of these years where we were working on this

That also could potentially undo any metabolic improvements that can go hand-in-hand with weight loss, such as in diabetes and blood pressure

These results have meaningful clinical and policy implications for Asian countries, where lower BMI thresholds define obesity compared to other populations

In Phase 2 trials published in The Lancet, patients on 0.5mg tesofensine lost an average of 11.3kg (about 10.6% body weight) over 24 weeksroughly double what was achieved with obesity medications available at that time