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Description
Clinical trials showed joint pain rates similar to placebo, indicating no established direct causal relationship

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8 The presence of neutrophils in all aspects of the bowel mucosa, immune cells in the lamina propria of the colonic mucosa, damage to the mucosal cells or snaps in the mucosal surface, the appearance of granulation tissue or exudation, interruptions of colonic crypts, and a decline in the number of mucosal goblet cells are clear indicators of active disease
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